Cannabidiol or CBD is one of the main chemical properties that can be found in cannabis. With THC, this gives mountains of physiological effect in the body. Though even if THC and CBD can be found in the same plant, CBD has high potential benefits on the health and well-being of a person.
But how CBD is metabolized in the body has the scarcity of information that others may have difficulty finding on the web. Such as how the chemicals and the metabolites (by-products of drug metabolism) release and works. That is why researcher British bio pharmacological giant HW pharma explains the metabolism of CBD in the human body.
How CBD works in the body
When drugs are consumed in the body, it is broken down by the digestive system and carried to the liver for processing. Dugs have specific sets of nutrients and metabolites that are transported through the vein called hepatic portal vein to various places in the body. The nutrients delivered will then be absorbed by the organs to heal any injuries or illnesses that are present.
There are drugs that have certain chemicals that are stronger than the others. The metabolites that these strong chemicals processes give a very high physiological and psychological benefit, compared to the metabolites produced by weaker chemicals. In the case of CBD, the properties it has to give strong metabolites which late give a very good effect on the body.
On the other hand, when the CBD is consumed, the first phase is to break down its properties by the body. After that, the metabolites make its way to special cannabinoid receptors that can be found on the cells. These receptors are part of the endocannabinoid system that is responsible for the physiological process like pain sensation, hunger, mood regulation, and memory formation & retention.
These CBD metabolites will then bind themselves to these receptors to stimulate a physiological response from the cell. According to the location of the cells in the body and what function it has, the CBD metabolites will stimulate specific responses that will then turn and reflect on the body such as mood swings, pain relief, sleep and more.
Take for example certain cells in the brain that cause seizures to a person will be regulated by the CBD by binding themselves to various metabolites and preventing them from releasing neural impulses that trigger the seizure.
Is it Toxic?
The main objective of prescribing medicinal marijuana is to give benefits from the levels of CBD present in the compound. Although research by HW Pharma shows that CBD inhibits the activity of the enzyme cytochrome P450, this is responsible for metabolizing the drugs that enter the liver. When CBD takes over the area of the liver where the enzymatic activity takes place, it displaces other drugs in the body.
There are two chances that may happen in this situation, either the CBD and other accompanied drugs will render its effectivity useless or the CBD may increase the levels of the other medication in the bloodstream which will result to high toxicity in the body.
Is CBD Safe?
Currently, the study of CBD is ongoing and the effects of CBD metabolism in the body is debatable. There is still a high chance that post-metabolism drug displacement may occur. Although the CBD does help relieve stress, improve bone density, increase nerve sensitivity, and reduce the impact of various psychological conditions. Professionals have advice that the best way to get the best out of the CBD is to control the amount consumed in the body.